Understanding Types of Hyperpigmentation: PIE, PIH, Melasma – and How to Treat Them Effectively
May 14, 2025Hyperpigmentation is among the most prevalent skin issues individuals encounter, yet it remains one of the most misunderstood. From reddish marks that linger after acne to enduring brown patches on the cheeks, various types of hyperpigmentation require unique treatments. In this comprehensive guide, we will explore the different forms of hyperpigmentation — including Post-Inflammatory Erythema (PIE), Post-Inflammatory Hyperpigmentation (PIH), and Melasma — their underlying causes, how to recognize them, and the most effective active ingredients and skincare routines to treat each type successfully. As always, Juicy Chemistry provides you with science-based, dermatologist-informed insights, all while adhering to a clean, certified organic approach to skincare.
1. Post-Inflammatory Erythema (PIE)
PIE manifests as pink, red, or purple marks that linger on the skin following a pimple or skin injury. This condition arises from damage to the blood vessels and capillaries beneath the skin, rather than from an overproduction of melanin.
🧬 Root Cause:
Damage to blood vessels due to inflammation
🎯 Best Suited Actives:
- Niacinamide: Renowned for its capacity to reduce inflammation, enhance barrier repair, and lessen redness.
- Azelaic Acid: Provides anti-inflammatory and vasoconstrictive properties, making it effective for soothing irritated skin.
- Centella Asiatica (CICA): Celebrated for its calming effects, it helps alleviate inflammation and supports skin healing.
🧖♀️ Routine Tips:
- Choose gentle, non-stripping cleansers to preserve the skin's natural barrier.
- Steer clear of excessive exfoliation to avoid further irritation.
- Regularly use serums that focus on barrier repair and calming ingredients to promote optimal skin health.
2. Post-Inflammatory Hyperpigmentation (PIH)
PIH is characterized by brown or black flat spots that remain after acne or skin trauma. This condition is more prevalent in medium to darker skin tones due to increased melanin production.
🧬 Root Cause:
Overactivity of melanocytes triggered by inflammation
🎯 Best Suited Actives:
- Alpha Arbutin: Aids in regulating melanin production by inhibiting the enzyme tyrosinase.
- Ectoine: Helps manage melanin production and combats oxidative stress.
- Niacinamide: Reduces the transfer of melanin to skin cells.
🧖♀️ Routine Tips:
- Integrate brightening serums into both your morning and evening skincare routines.
- Limit sun exposure and consistently apply SPF protection.
- Exercise patience, as post-inflammatory hyperpigmentation (PIH) generally improves over several weeks.
3. Melasma
Melasma is a chronic skin condition that appears as large, symmetrical patches of brown pigmentation, often triggered by hormonal changes, UV exposure, or genetic factors. It is notoriously challenging to treat and is prone to recurrence.
🧬 Root Cause:
Hormonal fluctuations, UV exposure, genetic predisposition, or a combination of these factors.
🎯 Best Suited Actives:
- Alpha Arbutin: Assists in reducing melanin, thereby diminishing the appearance of age spots, freckles, melasma, and PIH.
- Niacinamide: Provides anti-inflammatory benefits and helps regulate pigmentation.
- Azelaic Acid: A versatile ingredient that addresses both inflammation and pigmentation issues.
🧖♀️ Routine Tips:
- Incorporate active ingredients that reduce pigmentation into your daily skincare regimen.
- Always apply a broad-spectrum SPF to shield your skin from further UV damage.
- Layering with antioxidants and calming serums can enhance the overall benefits.
Conclusion
Recognizing the type of hyperpigmentation you have is the crucial first step in selecting the appropriate treatment. Juicy Chemistry’s new range of actives specifically targets these concerns with certified organic, clinically validated ingredients. From Azelaic Acid to Alpha Arbutin and Niacinamide, our powerful yet skin-friendly formulations are designed to gently and effectively diminish all forms of hyperpigmentation while being considerate of both your skin and the environment.
Research Papers:
- https://pubmed.ncbi.nlm.nih.gov/12100180/
- https://pmc.ncbi.nlm.nih.gov/articles/PMC9975535/
- https://www.sciencedirect.com/science/article/abs/pii/S0894113022001090
- https://pmc.ncbi.nlm.nih.gov/articles/PMC8301119/
- https://www.sciencedirect.com/science/article/pii/S1369703X13000168
- https://onlinelibrary.wiley.com/doi/10.1111/jocd.16562
- https://rsdjournal.org/index.php/rsd/article/view/33581
- https://pmc.ncbi.nlm.nih.gov/articles/PMC3667296/